Chelsea's busy fixture schedule means they face six games in the next 17 days before Christmas, which is surely going to be a major test of their squad depth.
The Chelsea goal on 18 minutes will be credited to Loftus-Cheek, whose shot was on target but heading comfortably into the gloves of Patricio before Conor Coady diverted it into the bottom corner with his head to gift the England midfielder a second in as many matches.
And it looked as though his contribution could prove decisive until the hosts struck twice in four minutes at a raucous Molineux.
Chelsea head coach Maurizio Sarri criticised his players' attitude and felt they were overconfident after a shock 2-1 loss to Wolves on Wednesday.
Loftus-Cheek has all the physical attributes - speed, strength, height - and his technical ability on the ball is impressive. Willian and Alvaro Morata line up in attack alongside Eden Hazard, with Pedro and Olivier Giroud dropping to the bench. While Chelsea are looking to build on their win against Fulham over the weekend.
What does it mean? Sarri has repeatedly distanced his side from title talk and it is hard to disagree. Hazard continued to look risky, fizzing a shot narrowly over late on, but he has not found the net since October 7.
The Premier League match between Wolves and Chelsea will be broadcast online.
So will Chelsea supporters get to watch rarely-seen player Ethan Ampadu in the first team? The Italian admitted he was "really worried" by what he had seen thereafter as Wolves turned the game on its head through Diogo Jota's victor. He is joined in the centre by Loftus-Cheek, who deserves a go from the beginning in the Premier League.