Gano's third field goal of the game put the Panthers up 30-24 with just more than two minutes remaining.
It's the second year in a row the Giants (1-4) have been beaten by a monster field goal at the end. His previous career-long was a 59-yarder he hit in 2011 when he was with the Redskins. Olsen will give Newton his favorite target after a two-interception performance that kept this one in jeopardy until the end. Christian McCaffrey had 93 yards from scrimmage and an 18-yard touchdown catch for the Panthers (3-1).
Getting second-year wide receiver Curtis Samuel back on Sunday, after he sat out the first three games following a procedure for an irregular heartbeat, also was big.
Reid, who signed a one-year contract with the Panthers last week, claimed at the beginning of the offseason that he wasn't receiving interest from teams due to his decision to kneel during the national anthem.
Giants: Right tackle Chad Wheeler left in the fourth quarter with a hand injury and did not return. But it was sloppy play by the Giants - and a dubious unnecessary roughness call by the referees - that helped the Panthers salt the game away in the fourth quarter. Center Ryan Kalil was shaken up late in the fourth quarter and did not return as Tyler Larsen finished the game.