As a result, United have opted to look elsewhere for a new signing with Mourinho seemingly desperate to strengthen the central defence before the transfer deadline.
Alderweireld has entered the final 12 months of his contract but Spurs are demanding in excess of £60m for his signature. However, understandably Tottenham are holding out for as much money as they get for the defender.
Alderweireld has developed a reputation as one of the best centre-backs in the Premier League in recent years.
Spurs have a relatively strict wage structure compared to their top six rivals, so were unwilling to meet his wages demands.
Jose Mourinho has been looking to strengthen his options in central defence ahead of the new season and the Colombia worldwide is on the United manager's shortlist. Now Mourinho will know he needs to deliver more.
Antonio Valencia and Ashley Young - both ageing, converted wingers - start at full back, while England internationals Phil Jones and Chris Smalling have both failed to take numerous chances to show they are capable of playing at the highest level. Alderweireld's reassuring presence would make a major difference in that backline.
The Star reports that super-agent Mino Raiola will "tell United he can broker a £100m deal for Pogba with Barcelona", which would earn the Red Devils a tidy £11m profit on the £89m they paid Juventus two years ago.
Although the centre-half featured sparsely last season after a falling out with Mauricio Pochettino, Alderweireld is still a top-class defensive option and cannot simply be replaced in the pecking order by the likes of Cameron Carter-Vickers.